What is GBS?

Guillain-Barré (Ghee-yan Bah-ray) Syndrome is an inflammatory disorder of the peripheral nerves outside the brain and spinal cord.
It’s also called:
GBS is characterized by the rapid onset of numbness, weakness, and often paralysis of the legs, arms, breathing muscles, and face. Paralysis is ascending, meaning that it travels up the limbs from fingers and toes towards the torso.
GBS came to public attention briefly when it struck a number of people who received the 1976 swine flu vaccine. Although not in the news as much today, it continues to claim thousands of new victims each year, striking any one at any age, regardless of gender or ethnic background.
The rapid onset of weakness, frequently accompanied by abnormal sensations (numbness, tingling) that affect both sides of the body similarly, is common. Loss of reflexes, such as the knee jerk, are usually found.
It’s also called:
- Acute Inflammatory Demyelinating Polyneuropathy
- Landry’s Ascending Paralysis
GBS is characterized by the rapid onset of numbness, weakness, and often paralysis of the legs, arms, breathing muscles, and face. Paralysis is ascending, meaning that it travels up the limbs from fingers and toes towards the torso.
GBS came to public attention briefly when it struck a number of people who received the 1976 swine flu vaccine. Although not in the news as much today, it continues to claim thousands of new victims each year, striking any one at any age, regardless of gender or ethnic background.
The rapid onset of weakness, frequently accompanied by abnormal sensations (numbness, tingling) that affect both sides of the body similarly, is common. Loss of reflexes, such as the knee jerk, are usually found.
Are there different types?
There are many variants of GBS, but they all share the characteristic of being ‘rapid onset’:
- Acute Inflammatory Demyelinating Polyneuropathy (AIDP) 75% – 80% of cases fall into this ‘classic’ category
- Acute Motor Axonal Neuropathy (AMAN) Similar to AIDP, but without sensory symptoms
- Acute Motor Sensory Axonal Neuropathy (AMSAN) Severe variant of GBS more prevalent in Asia, Central America, and South America
- Miller Fisher Syndrome Characterized by double vision, loss of balance, and deep tendon reflexes
Is it hereditary?
There is no research to support that GBS or CIDP is contagious or hereditary.